Sakitamiwa Classification May 2026

This transition indicates that medical treatment or natural recovery is effectively closing the wound.

At this point, the ulcer is considered "endoscopically cured" because the mucosal defect has vanished.

The is a standardized endoscopic grading system used primarily by gastroenterologists to assess the life cycle and healing stages of peptic ulcers (both gastric and duodenal). Developed by Japanese researchers Sakita and Miwa, it divides the progression of an ulcer into three main stages— Active (A) , Healing (H) , and Scarring (S) —each further subdivided into two substages. sakitamiwa classification

This classification is a critical tool in clinical trials to evaluate the efficacy of acid-suppressing drugs like Proton Pump Inhibitors (PPIs) and Potassium-Competitive Acid Blockers (P-CABs) .

Over weeks or months, the redness fades into a white or pale scar as the tissue matures. This marks the final stage of healing. Clinical Utility and Scoring This transition indicates that medical treatment or natural

The ulcer base is completely covered by new epithelium, but the area remains red and vascularized. This is a "fresh" scar.

The system tracks an ulcer from its most aggressive, open state to its final resolution as a healed scar. Developed by Japanese researchers Sakita and Miwa, it

The ulcer is deep with a thick, white or yellowish-gray coating (slough) at the base. The margins are sharp and often swollen with edema.