The release of changed how mods are handled, causing many to break on updated versions.

: Navigate to your local documents folder, typically found at C:\Users\[Username]\Documents\My Games\Binding of Isaac Repentance\mods .

Find the options.ini file in your My Games\Binding of Isaac Repentance folder. Open it with a text editor and find the line EnableMods=0 . Change the value to EnableMods=1 and save the file. 3. Understanding the "Patched" Mods Issue (Repentance+)