The Binding of Isaac: Repentance remains a powerhouse in the indie roguelike scene, largely due to its massive modding community. While the Steam Workshop is the most common way to get these mods, players on other platforms—or those who prefer manual control—can still enjoy an updated and enhanced experience. How to Install Mods Without Steam

Significantly speeds up animations for slot machines, blood banks, and beggars, reducing the "min-maxing" downtime during runs.

A massive content mod that adds hundreds of new enemies, bosses, and items. Note that this is a "heavy" mod and requires a capable PC to run smoothly alongside others. YouTube·Vicfis